All minority populations showed a lower rate of diagnosis that fell short of statistical significance. Patients with migraines and patients classified as Caucasian had higher odds of being diagnosed with TGA. TGA was associated with lower hospital charges ($14,242 versus $21,319), shorter hospital stays (mean days: 2.49 versus 4.72 ), and routine hospital discharges (91.4% versus 74.5%). The odds of being diagnosed with TGA was lower among African Americans and Hispanics as well as among patients classified as Asian/Other, compared with Caucasians. Similarly, patients with TGA were more likely to have hypertension, precerebral disease, and hyperlipidemia. Patients with migraines were 5.98 times more likely to also have a diagnosis of TGA compared with patients without migraines. Descriptive and survey logistic regression analyses were conducted and adjusted for influence of comorbidities, demographic characteristics, and hospitalization-related factors. Data were obtained from the Nationwide Inpatient Sample using ICD-9 and procedure codes. Whatever the cause, transient global amnesia can be upsetting.The purpose of this article was to explore sex- and race-specific variables and comorbidities associated with transient global amnesia (TGA) using a nationally representative database. "This doesn't explain why this would happen only once while we do this Valsalva maneuver many times during the day," he said. What this explanation doesn't cover is why most people with transient global amnesia experience it only once, Ameriso told Livescience. Oxygen-poor blood then "piles up" in the veins draining the brain, especially in central brain regions that are key to memory formation. The increased pressure increases the resistance to blood flowing down the jugular veins, and insufficient valves may allow deoxygenated blood to push back up the neck. This is called the "Valsalva maneuver," familiar as the "bearing down" people might do when lifting weights, defecating or even having sex. The best guess for what might be happening is that patients unwittingly trigger the transient global amnesia by raising the pressure inside their abdomens. Valves in the veins prevent blood from flowing backward toward the head, but if the valves don't close sufficiently, blood could seep back upward. This vein, which runs down the side of the neck, carries spent blood from the brain back to the heart. They found that 80 percent of the patients had what is called insufficiency of the valves in the jugular vein. In a January 2010 study published in the journal Stroke, Ameriso and his colleagues conducted sonograms of the necks of 142 patients who'd experienced transient global amnesia within the last week. The closest thing to an explanation researchers have for this sex-triggered amnesia is that the problem may not begin in the brain, but in the neck.
By the time she left the emergency room, her symptoms were almost gone. In the case of the 54-year-old woman at the Washington, D.C., hospital, the last day was a fog, and she had been forgetful and confused since having sex.Īs with most patients, the woman's brain scans using magnetic resonance imaging (MRI) and computed tomography (CT) showed nothing unusual and no damage to the brain. Sometimes, people also experience transient retrograde amnesia, forgetting some portion of their previous memories. In most cases, the amnesia is anterograde, meaning people have trouble forming new memories.
People in their 50s and 60s are the most likely to experience an episode, but strangely, most people with transient global amnesia have it only once. Sex can trigger transient global amnesia, as can other physically strenuous activities.
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